Cancer сells shut down 'quality control' in DNA synthesis
DNA fracturing leads to accumulation of mutations in cells and is one of the causes of cancer. DNA restoration or repair, in scientific terminology, can prevent mutations and cancer development, but can also restore the viability of tumor cells damaged by chemotherapy and radiotherapy. A team of scientists led by Anton Buzdin, head of the Laboratory of Translational Genomic Bioinformatics at MIPT, has studied the characteristics of DNA repair in cancer and normal cells. The results of the study are published in the new journal Heliyon of the prestigious scientific publisher Cell Press.